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Multi-resolution graph-based analysis of histopathological whole slide images: application to mitotic cell extraction and visualization

Vincent Roullier 1 Olivier Lezoray 1 Vinh Thong Ta 2 Abderrahim Elmoataz 1
1 Equipe Image - Laboratoire GREYC - UMR6072
GREYC - Groupe de Recherche en Informatique, Image, Automatique et Instrumentation de Caen
Abstract : n this paper, we present a graph-based multi-resolution approach for mitosis extraction in breast cancer histological whole slide images. The proposed segmentation uses a multi-resolution approach which reproduces the slide examination done by a pathologist. Each resolution level is analyzed with a focus of attention resulting from a coarser resolution level analysis. At each resolution level, a spatial refinement by label regularization is performed to obtain more accurate segmentation around boundaries. The proposed segmentation is fully unsupervised by using domain specific knowledge.
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https://hal.archives-ouvertes.fr/hal-00708976
Contributor : Vinh-Thong Ta <>
Submitted on : Saturday, June 16, 2012 - 2:29:08 PM
Last modification on : Wednesday, November 13, 2019 - 3:41:21 PM

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  • HAL Id : hal-00708976, version 1

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Vincent Roullier, Olivier Lezoray, Vinh Thong Ta, Abderrahim Elmoataz. Multi-resolution graph-based analysis of histopathological whole slide images: application to mitotic cell extraction and visualization. Computerized Medical Imaging and Graphics, Elsevier, 2011, 35, pp.603-615. ⟨hal-00708976⟩

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