Fragment-based design of small RNA binders: promising developments and contribution of NMR.

Abstract : Fragment-based drug design has become increasingly popular over the last decade. We review here the use of this approach to design small RNA binders. In addition, we discuss the use of NMR to detect the binding of small molecules on RNA targets and to guide chemists in the design of compounds targeting RNA.
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Article dans une revue
Biochimie, Elsevier, 2012, 94 (7), pp.1607-1619. 〈10.1016/j.biochi.2012.02.002〉
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Soumis le : lundi 30 avril 2012 - 09:56:20
Dernière modification le : jeudi 22 novembre 2018 - 14:38:19

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Roba Moumné, Marjorie Catala, Valéry Larue, Laurent Micouin, Carine Tisné. Fragment-based design of small RNA binders: promising developments and contribution of NMR.. Biochimie, Elsevier, 2012, 94 (7), pp.1607-1619. 〈10.1016/j.biochi.2012.02.002〉. 〈hal-00692356〉

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