1,2-Dicarbonyl Compounds as Pronucleophiles in Organocatalytic Asymmetric Transformations

Wilfried Raimondi (1) , Damien Bonne (1) , Jean Rodriguez (1)

1 STeRéO

Organocatalysis likes them too! 1,2-dicarbonyl compounds possess high synthetic potential because of their adjacent multiple reactive centers. Recent contributions indicate that these reactive species, with an appropriate activation mode, may also act as efficient pronucleophiles in asymmetric organocatalyzed sequential or domino transformations including C-C or C-N bond formation

Mots clés: 2-dicarbonyls; asymmetric catalysis; domino reactions; organocatalysis; pronucleophiles

Domaines: Chimie organique

Wilfried Raimondi, Damien Bonne, Jean Rodriguez. 1,2-Dicarbonyl Compounds as Pronucleophiles in Organocatalytic Asymmetric Transformations. Angewandte Chemie International Edition, 2012, 51, pp.40-42. ⟨10.1002/anie.201106741⟩. ⟨hal-00676949⟩