Synthesis and evaluation of triazole-linked poly(e-caprolactone)-graft-poly(2-methyl-2-oxazoline) copolymers as potential drug carriers - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Chemical Communications Année : 2012

Synthesis and evaluation of triazole-linked poly(e-caprolactone)-graft-poly(2-methyl-2-oxazoline) copolymers as potential drug carriers

Résumé

Well-defined graft copolymers were obtained using a coppercatalysed azide-alkyne Huisgen's cycloaddition click reaction from both biocompatible and non-toxic poly(e-caprolactone) and poly(2-methyl-2-oxazoline) homopolymers. Resulting amphiphilic copolymers proved to form micelles that could be used as potential drug carriers.

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Dates et versions

hal-00671757 , version 1 (18-02-2012)

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Guillerm Brieuc, Vincent Darcos, Vincent Lapinte, Sophie Monge, Jean Coudane, et al.. Synthesis and evaluation of triazole-linked poly(e-caprolactone)-graft-poly(2-methyl-2-oxazoline) copolymers as potential drug carriers. Chemical Communications, 2012, 48, pp.2879-2881. ⟨10.1039/c2cc30191a⟩. ⟨hal-00671757⟩
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