Cytochrome P450 3A activity in mothers and their neonates as determined by plasma 4β-hydroxycholesterol

Hanna Nylén (1) , Sofia Sergel (2) , Lisa Forsberg (2) , Synnöve Lindemalm (3) , Leif Bertilsson (4) , Katarina Wide (2) , Ulf Diczfalusy (2)

1 Division of Clinical Chemistry, Department of Laboratory Medicine
2 Division of Neuropediatrics, Department of CLINTEC
3 Division of Pediatrics, Department of CLINTEC
4 Division of Clinical Pharmacology, Department of Laboratory Medicine

Mots clés: 4β-hydroxycholesterol; Oxysterols; Neonate; CYP3A; Pregnancy; Enzyme activity

Hanna Nylén, Sofia Sergel, Lisa Forsberg, Synnöve Lindemalm, Leif Bertilsson, et al.. Cytochrome P450 3A activity in mothers and their neonates as determined by plasma 4β-hydroxycholesterol. European Journal of Clinical Pharmacology, 2011, 67 (7), pp.715-722. ⟨10.1007/s00228-010-0984-1⟩. ⟨hal-00661255⟩