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Article Dans Une Revue Nature Neuroscience Année : 2011

Neuronal activity drives matching of pre- and post-synaptic function during synapse maturation

Résumé

The structure and function of presynaptic and postsynaptic compartments varies dramatically within neurons, but little is known about how they are functionally arranged with respect to each other. We found that, although they are structurally correlated from the early moments of formation, synapses only gradually become functionally matched, and that this process is dependent on ongoing electrical activity.
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Dates et versions

hal-00637332 , version 1 (01-11-2011)

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Luoise Kay, Lawrence Humphreys, Britta J Eickholt, Juan Burrone. Neuronal activity drives matching of pre- and post-synaptic function during synapse maturation. Nature Neuroscience, 2011, ⟨10.1038/nn.2826⟩. ⟨hal-00637332⟩

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