Synthesis of Pyrimidine-Containing Nucleoside β-(R/S)-Hydroxyphosphonate Analogues
Résumé
A concise route to nucleoside β-hydroxyphosphonate analogues is described. The use of a nucleoside β-ketophosphonate as the key intermediate allowed both the (R) and (S) isomers of β-hydroxyphosphonate analogues in the pyrimidine series to be accessed. Such derivatives may be considered as stable mimics of 5
Domaines
Chimie organique
Fichier principal
European Journal of Organic Chemistry, 2011, 3794-3802_1 (1008.23 Ko)
Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)