Lanthanide complexes as imaging agents anchored on nano-sized particles of boehmite

Abstract : The synthesis of boehmite nanoparticles modified with lanthanides (Eu, Tb and Gd) is described. Their synthesis, characterization and in vitro assays with HeLa cells were performed. The nuclear magnetic relaxation dispersion (NMRD) profiles of the two chelating moieties were studied. Imaging data from laser scanning confocal fluorescence microscopy and flow cytometry revealed that the nanoscaffolds were taken up by the cells, distributed throughout the cytoplasm and showed no toxicity. This platform could represent an alternative to silica-based inert matrices as imaging vehicles.
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https://hal.archives-ouvertes.fr/hal-00614888
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Submitted on : Wednesday, August 17, 2011 - 11:26:37 AM
Last modification on : Friday, October 11, 2019 - 2:14:08 PM

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Estefania Delgado-Pinar, M. Teresa Albelda, Juan C. Frias, Olga Barreiro, Emilio Tejera, et al.. Lanthanide complexes as imaging agents anchored on nano-sized particles of boehmite. Dalton Transactions, Royal Society of Chemistry, 2011, 40 (24), pp.6451-6457. ⟨10.1039/c1dt10389j⟩. ⟨hal-00614888⟩

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