The 'T-cell-ness' of NK cells: unexpected similarities between NK cells and T cells.

Emilie Narni-Mancinelli (1) , Eric Vivier (1, 2) , Yann M Kerdiles (1)

1 CIML - Centre d'Immunologie de Marseille - Luminy
2 Service de Chirurgie

NK cells are considered as prototypical innate immune cells. However, recent discoveries have tended to refine the dogmatic concepts of innate and adaptive immunity. In many ways, NK cells are highly related to T cells and represent the closest innate immune cell lineage to adaptive immune cell populations. Here, we review the relationships between NK cells and T cells and discuss the recently described cell-intrinsic-adaptive features of NK cells.

Domaines: Immunologie

Emilie Narni-Mancinelli, Eric Vivier, Yann M Kerdiles. The 'T-cell-ness' of NK cells: unexpected similarities between NK cells and T cells.. International Immunology, 2011, 23 (7), pp.427-31. ⟨10.1093/intimm/dxr035⟩. ⟨hal-00611633⟩