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Pré-Publication, Document De Travail Année : 2011

On emergence times in competition processes

Résumé

The estimation of the time by which mutants adapted to control measures emerge is a new challenge in modern epidemiology. Here, we use competition processes, the extension of birth-death processes in higher dimensions, to study the time $S$ by which a particular type emerges in a controlled population through a spontaneous birth or mutation. We give some bounds for the tail of the probability distribution of $S$. Then using properties of quasi-stationary distributions, we give conditions for the existence of an initial law under which $S$ is exponentially distributed. Finally, we provide some examples of our model use for the estimation of the emergence time of pathogen mutants overcoming host resistance in a host-pathogen system.
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Dates et versions

hal-00595912 , version 1 (25-05-2011)
hal-00595912 , version 2 (03-06-2011)
hal-00595912 , version 3 (08-07-2011)
hal-00595912 , version 4 (15-11-2012)
hal-00595912 , version 5 (23-10-2013)

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Romain Bourget, Loïc Chaumont, Natalia Sapoukhina. On emergence times in competition processes. 2011. ⟨hal-00595912v3⟩

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