At the frontiers of surgery : review

Tahwinder Upile (1) , Waseem Jerjes (1) , Henricus Sterenborg (2) , Brian Wong (3) , Adel El-Naggar , Justus Ilgner , Ann Sandison , Max Witjes , Merrill Biel , Robert van Heen , Zaïd Hamdoon , Ann Gillenwater , Charles Mosse , Dominic Robinson , Christian Betz , Herbert Stepp , Lina Bolotine (4, 5) , Gordon Mckenzie , Hugh Barr , Zhongping Chen , Kristian Berg , Anil d'Cruz , Holger Sudhoff , Nicholas Stone , Catherine Kendall , Sheila Fisher , Alexander Macrobert (6) , Andreas Leunig , Malini Olivo , Rebecca Richards-Kortum , Khee Soo , Vanderlei Bagnato , Lin-Ping Choo-Smith , Katarina Svanberg , Bing Tan , Brian Wilson , Herbert Wolfsen , Irving Bigio (7) , Arjun Yodh , Colin Hopper (1)

1 UCL - University College of London [London]
2 Center for Optical Diagnostics and Therapy
3 Beckman Laser Institute
4 CRAN - Centre de Recherche en Automatique de Nancy
5 CAV - Centre Alexis Vautrin
6 National Medical Laser Center
7 BU - Boston University [Boston]

The complete surgical removal of disease is a desirable outcome particularly in oncology. Unfortunately much disease is microscopic and difficult to detect causing a liability to recurrence and worsened overall prognosis with attendant costs in terms of morbidity and mortality. It is hoped that by advances in optical diagnostic technology we could better define our surgical margin and so increase the rate of truly negative margins on the one hand and on the other hand to take out only the necessary amount of tissue and leave more unaffected non-diseased areas so preserving function of vital structures. The task has not been easy but progress is being made as exemplified by the presentations at the 2nd Scientific Meeting of the Head and Neck Optical Diagnostics Society (HNODS) in San Francisco in January 2010. We review the salient advances in the field and propose further directions of investigation

Domaines: Biophysique

Tahwinder Upile, Waseem Jerjes, Henricus Sterenborg, Brian Wong, Adel El-Naggar, et al.. At the frontiers of surgery : review. Head and Neck Oncology, 2011, 3, pp.7. ⟨10.1186/1758-3284-3-7⟩. ⟨hal-00567498⟩