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Changes in blood B cell phenotypes and Epstein-Barr virus load in chronically human immunodeficiency virus-infected patients before and after antiretroviral therapy.

Abstract : Because transitional-like B cells persist concomitantly with high EBV load after highly active antiretroviral therapy, we suggest that this population might be an alternative EBV reservoir in patients with chronic HIV infection who have strongly reduced numbers of memory B cells. The consequences of EBV infection of immature B cells are discussed with regard to B cell maturation and a higher prevalence of B cell lymphoma in HIV‐infected patients.
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https://hal.archives-ouvertes.fr/hal-00560997
Contributor : Claire Carrion <>
Submitted on : Monday, January 31, 2011 - 2:24:21 PM
Last modification on : Monday, January 22, 2018 - 11:12:36 AM

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Yolande Richard, Corinne Amiel, Vincent Jeantils, Denis Mestivier, Alain Portier, et al.. Changes in blood B cell phenotypes and Epstein-Barr virus load in chronically human immunodeficiency virus-infected patients before and after antiretroviral therapy.. Journal of Infectious Diseases, Oxford University Press (OUP), 2010, 202 (9), pp.1424-34. ⟨10.1086/656479⟩. ⟨hal-00560997⟩

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