Outcome of children with sickle cell disease admitted to intensive care - a single institution experience

Jack Luke Bartram (1) , Swee Lay Thein (2) , Kate Gardner (1) , Yaya Egberongbe (3) , Pam d'Silva (3) , Sue Height (1) , Moira C Dick (1, 4) , Sandra O'Driscoll (1) , David C Rees (5)

1 Department of Paediatric Haematology [London]
2 Head of Division of Gene and Cell Based Therapy
3 Department of Child Health
4 Paediatric Haematology
5 Paediatric Haematology

We retrospectively audited children with sickle cell disease admitted to paediatric intensive care (PICU) at King's College Hospital between January 2000 and December 2008. 46 children with SCD were admitted, on 49 separate occasions. Ages ranged from 4 months to 15 years (median 7.6 years). Three children died in PICU, however two presented to hospital in cardiorespiratory arrest; overall mortality was 6%. The most common reason for admission was acute chest syndrome (43%). 88% of admissions required blood transfusion, of which 74% had exchange blood transfusions. The mortality among children with SCD admitted to PICU is low.

Mots clés: Medicine

Jack Luke Bartram, Swee Lay Thein, Kate Gardner, Yaya Egberongbe, Pam d'Silva, et al.. Outcome of children with sickle cell disease admitted to intensive care - a single institution experience. British Journal of Haematology, 2010, 150 (5), pp.614. ⟨10.1111/j.1365-2141.2010.08272.x⟩. ⟨hal-00552602⟩