Synthesis and characterization of near-infrared Cu−In−Se/ZnS core/shell quantum dots for In vivo Imaging

Abstract : Near-infrared (NIR) semiconductor quantum dots (QDs) represent promising fluorescent probes for biological and biomedical imaging. CuInSe2 is a good candidate for these applications due to its bandgap in the near-infrared and the reduced toxicity of its components compared to other NIR QD materials (CdTe, CdHgTe, PbS, etc.). Here we present a simple one-pot synthetic route without injection to make fluorescent sphalerite Cu−In−Se core and Cu−In−Se/ZnS core/shell QDs. We show that the photoluminescence (PL) of the resulting core QDs can be tuned from 700 nm to 1 μm depending on the QD size (from 2 to 5 nm in diameter). The optical and structural properties of these QDs are consistent with charge recombination via donor−acceptor levels instead of direct excitonic recombination. Finally, we show that the growth of a ZnS shell around these QDs increases their PL quantum yield substantially (up to 40−50% at 800 nm) and allows preservation of their PL properties after solubilization into water and in vivo, as demonstrated by detection of the regional lymph node in a mouse.
Type de document :
Article dans une revue
Chemistry of Materials, American Chemical Society, 2010, 22 (22), pp.6117-6124. 〈10.1021/cm101881b〉
Liste complète des métadonnées

https://hal.archives-ouvertes.fr/hal-00548762
Contributeur : Didier Wolf <>
Soumis le : lundi 20 décembre 2010 - 13:24:22
Dernière modification le : mercredi 21 mars 2018 - 18:57:44

Identifiants

Collections

Citation

Elsa Cassette, Thomas Pons, Cécile Bouet, Marion Helle, Lina Bezdetnaya, et al.. Synthesis and characterization of near-infrared Cu−In−Se/ZnS core/shell quantum dots for In vivo Imaging. Chemistry of Materials, American Chemical Society, 2010, 22 (22), pp.6117-6124. 〈10.1021/cm101881b〉. 〈hal-00548762〉

Partager

Métriques

Consultations de la notice

229