Motion artifact suppression in full-field optical coherence tomography

Delphine Sacchet (1) , Michal Brzezinski (1) , Julien Moreau (2) , Arnaud Dubois (3)

1 Laboratoire Charles Fabry de l'Institut d'Optique / Elsa
2 Laboratoire Charles Fabry de l'Institut d'Optique / Macsybio - bio
3 Laboratoire Charles Fabry de l'Institut d'Optique / Elsa - bio

Significant motion artifacts limit the performance of conventional full-field optical coherence tomography (FF-OCT) for in vivo imaging. We present a theoretical and experimental study of those limitations. A new FF-OCT system suppressing most of artifacts due to sample motions is demonstrated using instantaneous phase shifting with nonpolarizing optics and pulsed illumination. The experimental setup is based on a Linnik-type interferometer illuminated by the superluminescence emission from a Ti∶Al2O3 waveguide crystal. En face tomographic images are calculated as a combination of two phase-opposed interferometric images acquired simultaneously by two CCD cameras placed at both outputs of the interferometer, with a spatial resolution of 0:8 μm×1:6 μm (axial × transverse) and a detection sensitivity of ∼60 dB

Domaines: Optique [physics.optics]

Delphine Sacchet, Michal Brzezinski, Julien Moreau, Arnaud Dubois. Motion artifact suppression in full-field optical coherence tomography. Applied optics, 2010, 49 (9), pp.1480-1488. ⟨hal-00520528⟩