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Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol.

Abstract : 7β-OH, 7KC, and 25-OH have cytotoxic, oxidative, inflammatory, and/or angiogenic activities on ARPE-19 cells. As Rsv has some protective effects against oxysterol-induced cell death and VEGF secretion it could be valuable in ARMD treatment.
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https://hal.archives-ouvertes.fr/hal-00514897
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Submitted on : Friday, September 3, 2010 - 4:06:37 PM
Last modification on : Sunday, June 26, 2022 - 1:52:38 AM
Long-term archiving on: : Saturday, December 4, 2010 - 2:52:33 AM

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B. Dugas, Soeli Charbonnier, Mauhamad Baarine, Kevin Ragot, Dominique Delmas, et al.. Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol.. European Journal of Nutrition, Springer Verlag, 2010, 49 (7), pp.435-46. ⟨10.1007/s00394-010-0102-2⟩. ⟨hal-00514897⟩

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