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Structural and functional diversity of native brain neuronal nicotinic receptors

Abstract : Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand-gated ion channels present in the central and peripheral nervous systems, that are permeable to mono-and divalent cations. They share a common basic structure but their pharmacological and functional properties arise from the wide range of different subunit combinations making up distinctive subtypes.
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Submitted on : Friday, August 13, 2010 - 2:50:57 AM
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Cecilia Gotti, Francesco Clementi, Alice Fornari, Annalisa Gaimarri, Stefania Guiducci, et al.. Structural and functional diversity of native brain neuronal nicotinic receptors. Biochemical Pharmacology, Elsevier, 2009, 78 (7), pp.703. ⟨10.1016/j.bcp.2009.05.024⟩. ⟨hal-00509504⟩

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