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Article Dans Une Revue Journal of Magnetic Resonance Année : 2010

An alternative scheme for the multiplexed acquisition of 1D and 2D NMR spectra.

Résumé

Spin system selective 1D (1)H, 2D DQF-COSY and 2D HSQC NMR spectra were recorded in order to fully assign the (1)H and (13)C 1D NMR spectra of an asymmetrical beta-cyclodextrin derivative. Instead of individually accessing the seven sugar anomeric protons by means of long multiplet selective pulses, only short region selective pulses were used. The simultaneously selected anomeric protons were differentiated by allowing their magnetization to evolve under the sole effect of the chemical shift interaction. In each experiment, the seven recorded spectra were linear combinations of the seven desired ones. The combination coefficients were measured and used to obtain almost perfectly separated sugar unit sub-spectra. This multiplexed acquisition scheme resulted in a time gain factor of about 2.

Dates et versions

hal-00508828 , version 1 (06-08-2010)

Identifiants

Citer

B. Plainchont, A. Martinez, S. Tisse, J.-P. Bouillon, J.-M. Wieruszeski, et al.. An alternative scheme for the multiplexed acquisition of 1D and 2D NMR spectra.. Journal of Magnetic Resonance, 2010, epub ahead of print. ⟨10.1016/j.jmr.2010.06.005⟩. ⟨hal-00508828⟩
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