Manganese- or iron-catalyzed homocoupling of Grignard reagents using atmospheric oxygen as an oxidant

G. Cahiez (1) , A. Moyeux (1) , J. L. Buendia , C. Duplais

1 CSPBAT - Chimie, Structures et Propriétés de Biomatériaux et d'Agents Thérapeutiques

Atmospheric oxygen was used for the first time as an oxidant in metal-catalyzed homocoupling of Grignard reagents. These manganese- or iron-catalyzed reactions are efficient, cheap, and eco-friendly. They are applicable to the large-scale synthesis of symmetrical conjugated compounds.

Mots clés: ALKYL-HALIDES; ORGANOMAGNESIUM COMPOUNDS; BETA-HYDROGENS

G. Cahiez, A. Moyeux, J. L. Buendia, C. Duplais. Manganese- or iron-catalyzed homocoupling of Grignard reagents using atmospheric oxygen as an oxidant. Journal of the American Chemical Society, 2007, 129 (45), pp.13788-13789. ⟨10.1021/ja075417k⟩. ⟨hal-00462611⟩