Comparing Bacterial Genomes by Searching their Common Intervals

Abstract : Comparing bacterial genomes implies the use of a dedicated measure. It relies on comparing circular genomes based on a set of conserved genes. Following this assumption, the common interval appears to be a good candidate. For evidences, we propose herein an approach to compute the common intervals between two circular genomes that takes into account duplications. Its application on a concrete case, comparing E. coli and V. cholerae, is accurate. It indeed emphasizes sets of conserved genes that present high impacts on bacterial functions.
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Sébastien Angibaud, Damien Eveillard, Guillaume Fertin, Irena Rusu. Comparing Bacterial Genomes by Searching their Common Intervals. Springer-Verlag. 1st International Conference on Bioinformatics and Computational Biology (BICoB 2009), 2009, New Orleans, United States. Springer-Verlag, Lecture Notes in BioInformatics (LNBI) (5462), pp.102-113, 2009, Lecture Notes in BioInformatics (LNBI). 〈hal-00416466〉

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