Decreased hemispheric water mobility in hemiplegic migraine related to mutation of CACNA1A gene. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Neurology Année : 2000

Decreased hemispheric water mobility in hemiplegic migraine related to mutation of CACNA1A gene.

Résumé

We report a reversible reduction of water diffusion in the brain during a prolonged attack of hemiplegic migraine. The patient had a sporadic mutation of the CACNA1A gene. The diffusion changes were observed in the contralateral hemisphere 3 and 5 weeks after the onset of hemiplegia. These results suggest the occurrence of hemispheric cytotoxic edema during severe attacks of hemiplegic aura. The mechanisms underlying such ultrastructural modifications are unknown but an abnormal release of excitatory amino acids can be hypothesized.

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Dates et versions

hal-00349841 , version 1 (04-01-2009)

Identifiants

  • HAL Id : hal-00349841 , version 1
  • PUBMED : 10668728

Citer

H. Chabriat, K. Vahedi, C. A. Clark, Cyril Poupon, A. Ducros, et al.. Decreased hemispheric water mobility in hemiplegic migraine related to mutation of CACNA1A gene.. Neurology, 2000, 54 (2), pp.510-2. ⟨hal-00349841⟩
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