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About MEA impedance measurement and analysis

Abstract : The electrode impedance Z is an important parameter for the MEA detection of neural activity. Beside the commonly admitted fact that a low Z at 1 kHz increases the signal to noise ratio, the knowledge of the Z(f) variation inside a larger frequency range is essential to simulate realistic extra-cellular data suitable for validation of spike sorting algorithms. We have thus built an experimental set-up allowing an automated MEA impedance spectroscopy. It appears clearly that Z cannot be simply described by classical electrical circuits : electrochemical circuits including for example Warburg impedance show better concordance with experimental data. Lastly, great care must be taken when giving a Z value, as it is for example strongly time dependent.
keyword : impedance MEA
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https://hal.archives-ouvertes.fr/hal-00318561
Contributor : Guillaume Becq <>
Submitted on : Thursday, September 4, 2008 - 11:54:38 AM
Last modification on : Wednesday, December 30, 2020 - 10:58:02 AM
Long-term archiving on: : Thursday, June 3, 2010 - 7:57:12 PM

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Guillaume Becq, Guillaume Bienkowski, Jean-Paul Diard, Catherine Villard. About MEA impedance measurement and analysis. 6th international meeting on substrate-integrated micro electrode arrays, Jul 2008, Reutlingen, Germany. pp.277-278. ⟨hal-00318561⟩

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