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Article Dans Une Revue Journal of Chromatography A Année : 2007

Selective sample treatment using molecularly imprinted polymers

Résumé

The molecularly imprinted polymers (MIPs) are synthetic polymers possessing specific cavities designed for a target molecule. By a mechanism of molecular recognition, the MIPs are used as selective sorbents for the solid-phase extraction of target analytes from complex matrices. MIPs are often called synthetic antibodies in comparison with immuno-based sorbents; they offer some advantages including easy, cheap and rapid preparation and high thermal and chemical stability. This review describes the use of MIPs in solid-phase extraction with emphasis on their synthesis, the various parameters affecting the selectivity of the extraction, their potential to selectively extract analytes from complex aqueous samples or organic extracts, their on-line coupling with LC and their potential in miniaturized devices.
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Dates et versions

hal-00261614 , version 1 (07-03-2008)

Identifiants

  • HAL Id : hal-00261614 , version 1

Citer

Valérie Pichon. Selective sample treatment using molecularly imprinted polymers. Journal of Chromatography A, 2007, 1152, pp.41-53. ⟨hal-00261614⟩
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