A. D. Howard, G. Mcallister, S. D. Feighner, Q. Liu, R. P. Nargund et al., Orphan G-protein-coupled receptors and natural ligand discovery, Trends in Pharmacological Sciences, vol.22, issue.3, pp.132-140, 2001.
DOI : 10.1016/S0165-6147(00)01636-9

R. Seifert and K. Wenzel-seifert, Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors, Naunyn-Schmiedeberg's Archives of Pharmacology, vol.366, issue.5, pp.381-416, 2002.
DOI : 10.1007/s00210-002-0588-0

G. Milligan and R. A. Bond, Inverse agonism and the regulation of receptor number, Trends in Pharmacological Sciences, vol.18, issue.12, pp.468-474, 1997.
DOI : 10.1016/S0165-6147(97)01139-5

L. A. Matsuda, S. J. Lolait, M. J. Brownstein, A. C. Young, and T. I. Bonner, Structure of a cannabinoid receptor and functional expression of the cloned cDNA, Nature, vol.346, issue.6284, pp.561-564, 1990.
DOI : 10.1038/346561a0

A. C. Howlett, F. Barth, T. I. Bonner, G. Cabral, P. Casellas et al., International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors, Pharmacological Reviews, vol.54, issue.2, pp.161-202, 2002.
DOI : 10.1124/pr.54.2.161

M. Bouaboula, S. Perrachon, L. Milligan, X. Canat, M. Rinaldi-carmona et al., A Selective Inverse Agonist for Central Cannabinoid Receptor Inhibits Mitogen-activated Protein Kinase Activation Stimulated by Insulin or Insulin-like Growth Factor 1, Journal of Biological Chemistry, vol.268, issue.35, pp.22330-22339, 1997.
DOI : 10.1038/365652a0

X. Pan, S. R. Ikeda, L. , and D. L. , Currents by Reversal of Tonic CB1 Cannabinoid Receptor Activity, Molecular Pharmacology, vol.54, issue.6, pp.1064-1072, 1998.
DOI : 10.1124/mol.54.6.1064

C. J. Hillard, S. Muthian, and C. S. Kearn, cannabinoid receptor activation on cerebellar granule cell nitric oxide synthase activity, FEBS Letters, vol.11, issue.3, pp.277-281, 1999.
DOI : 10.1016/S0898-6568(98)00060-6

URL : http://onlinelibrary.wiley.com/doi/10.1016/S0014-5793(99)01253-3/pdf

S. Marion, D. M. Weiner, C. , and M. G. , RNA Editing Induces Variation in Desensitization and Trafficking of 5-Hydroxytryptamine 2c Receptor Isoforms, Journal of Biological Chemistry, vol.53, issue.4, pp.2945-2954, 2004.
DOI : 10.1073/pnas.011303698

S. Miserey-lenkei, C. Parnot, S. Bardin, P. Corvol, and E. Clauser, Receptor Mutants Is Blocked by Inverse Agonists, Journal of Biological Chemistry, vol.269, issue.8, pp.5891-5901, 2002.
DOI : 10.1073/pnas.90.11.5133

URL : http://www.jbc.org/content/277/8/5891.full.pdf

T. Kobayashi, E. Stang, K. S. Fang, P. De-moerloose, R. G. Parton et al., A lipid associated with the antiphospholipid syndrome regulates endosome structure and function, Nature, vol.89, issue.6672, pp.193-197, 1998.
DOI : 10.1016/S0022-5320(84)80024-6

L. Hunyady, A. J. Baukal, Z. Gaborik, J. A. Olivares-reyes, M. Bor et al., angiotensin receptor, The Journal of Cell Biology, vol.112, issue.7, pp.1211-1222, 2002.
DOI : 10.1074/jbc.271.31.18302

M. Darmon, X. Langlois, L. Suffisseau, C. M. Fattaccini, and M. Hamon, Differential Membrane Targeting and Pharmacological Characterization of Chimeras of Rat Serotonin 5-HT1A and 5-HT1B Receptors Expressed in Epithelial LLC-PK1 Cells, Journal of Neurochemistry, vol.71, issue.6, pp.2294-2303, 1998.
DOI : 10.1046/j.1471-4159.1998.71062294.x

T. M. Savino, J. Gebrane-younes, J. De-mey, J. B. Sibarita, and D. Hernandez-verdun, Nucleolar Assembly of the Rrna Processing Machinery in Living Cells, The Journal of Cell Biology, vol.73, issue.5, pp.1097-1110, 2001.
DOI : 10.1007/s004120050203

Z. Lenkei, A. Beaudet, N. Chartrel, N. De-mota, T. Irinopoulou et al., A Highly Sensitive Quantitative Cytosensor Technique for the Identification of Receptor Ligands in Tissue Extracts, Journal of Histochemistry & Cytochemistry, vol.268, issue.11, pp.1553-1564, 2000.
DOI : 10.1111/j.1471-4159.1989.tb07276.x

R. S. Landsman, T. H. Burkey, P. Consroe, W. R. Roeske, Y. et al., SR141716A is an inverse agonist at the human cannabinoid CB1 receptor, European Journal of Pharmacology, vol.334, issue.1, pp.1-2, 1997.
DOI : 10.1016/S0014-2999(97)01160-6

C. Hsieh, S. Brown, C. Derleth, and K. Mackie, Internalization and Recycling of the CB1 Cannabinoid Receptor, Journal of Neurochemistry, vol.126, issue.9, pp.493-501, 1999.
DOI : 10.7326/0003-4819-126-10-199705150-00008

J. P. Roche, S. Bounds, S. Brown, and K. Mackie, A Mutation in the Second Transmembrane Region of the CB1 Receptor Selectively Disrupts G Protein Signaling and Prevents Receptor Internalization, Molecular Pharmacology, vol.56, issue.3, pp.611-618, 1999.
DOI : 10.1124/mol.56.3.611

C. Baratti-elbaz, N. Ghinea, O. Lahuna, H. Loosfelt, C. Pichon et al., Internalization and Recycling Pathways of the Thyrotropin Receptor, Molecular Endocrinology, vol.13, issue.10, pp.1751-1765, 1999.
DOI : 10.1210/mend.13.10.0360

P. Tsao, T. Cao, V. Zastrow, and M. , Role of endocytosis in mediating downregulation of G-protein-coupled receptors, Trends in Pharmacological Sciences, vol.22, issue.2, pp.91-96, 2001.
DOI : 10.1016/S0165-6147(00)01620-5

A. Subtil, I. Gaidarov, K. Kobylarz, M. A. Lampson, J. H. Keen et al., Acute cholesterol depletion inhibits clathrin-coated pit budding, Proceedings of the National Academy of Sciences, vol.10, issue.4, pp.6775-6780, 1999.
DOI : 10.1091/mbc.10.4.961

URL : http://www.pnas.org/content/96/12/6775.full.pdf

E. M. Van-dam and W. Stoorvogel, Dynamin-dependent Transferrin Receptor Recycling by Endosome-derived Clathrin-coated Vesicles, Molecular Biology of the Cell, vol.13, issue.1, pp.169-182, 2002.
DOI : 10.1091/mbc.01-07-0380

E. M. Van-dam, T. Ten-broeke, K. Jansen, P. Spijkers, and W. Stoorvogel, Endocytosed Transferrin Receptors Recycle via Distinct Dynamin and Phosphatidylinositol 3-Kinase-dependent Pathways, Journal of Biological Chemistry, vol.261, issue.50, pp.48876-48883, 2002.
DOI : 10.1042/0264-6021:3550249

M. Zerial and H. Mcbride, Rab proteins as membrane organizers, Nature Reviews Molecular Cell Biology, vol.274, issue.2, pp.107-117, 2001.
DOI : 10.1074/jbc.274.41.28857

C. Bucci, R. G. Parton, I. H. Mather, H. Stunnenberg, K. Simons et al., The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway, Cell, vol.70, issue.5, pp.715-728, 1992.
DOI : 10.1016/0092-8674(92)90306-W

O. Ullrich, S. Reinsch, S. Urbe, M. Zerial, and R. G. Parton, Rab11 regulates recycling through the pericentriolar recycling endosome, The Journal of Cell Biology, vol.135, issue.4, pp.913-924, 1996.
DOI : 10.1083/jcb.135.4.913

P. Van-der-sluijs, M. Hull, P. Webster, P. Male, B. Goud et al., The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway, Cell, vol.70, issue.5, pp.729-740, 1992.
DOI : 10.1016/0092-8674(92)90307-X

J. L. Seachrist, F. , and S. S. , Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases, Life Sciences, vol.74, issue.2-3, pp.225-235, 2003.
DOI : 10.1016/j.lfs.2003.09.009

J. L. Seachrist, S. A. Laporte, L. B. Dale, A. V. Babwah, M. G. Caron et al., Rab5 Association with the Angiotensin II Type 1A Receptor Promotes Rab5 GTP Binding and Vesicular Fusion, Journal of Biological Chemistry, vol.113, issue.1, pp.679-685, 2002.
DOI : 10.1038/32937

B. Sonnichsen, S. De-renzis, E. Nielsen, J. Rietdorf, and M. Zerial, Distinct Membrane Domains on Endosomes in the Recycling Pathway Visualized by Multicolor Imaging of Rab4, Rab5, and Rab11, The Journal of Cell Biology, vol.112, issue.4, pp.901-914, 2000.
DOI : 10.1083/jcb.140.5.1039

J. Lippincott-schwartz and C. L. Smith, Insights into secretory and endocytic membrane traffic using green fluorescent protein chimeras, Current Opinion in Neurobiology, vol.7, issue.5, pp.631-639, 1997.
DOI : 10.1016/S0959-4388(97)80082-7

C. J. Daly and J. C. Mcgrath, Fluorescent ligands, antibodies, and proteins for the study of receptors, Pharmacology & Therapeutics, vol.100, issue.2, pp.101-118, 2003.
DOI : 10.1016/j.pharmthera.2003.08.001

L. Kallal and J. L. Benovic, Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking, Trends in Pharmacological Sciences, vol.21, issue.5, pp.175-180, 2000.
DOI : 10.1016/S0165-6147(00)01477-2

J. P. Morello, A. Salahpour, A. Laperriere, V. Bernier, M. F. Arthus et al., Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants, Journal of Clinical Investigation, vol.105, issue.7, pp.887-895, 2000.
DOI : 10.1172/JCI8688

U. E. Petaja-repo, M. Hogue, A. Laperriere, P. Walker, and M. Bouvier, Export from the Endoplasmic Reticulum Represents the Limiting Step in the Maturation and Cell Surface Expression of the Human ?? Opioid Receptor, Journal of Biological Chemistry, vol.269, issue.18, pp.13727-13736, 2000.
DOI : 10.1021/bi952290f

T. T. Cao, R. W. Mays, V. Zastrow, and M. , Regulated Endocytosis of G-protein-coupled Receptors by a Biochemically and Functionally Distinct Subpopulation of Clathrin-coated Pits, Journal of Biological Chemistry, vol.1136, issue.38, pp.24592-24602, 1998.
DOI : 10.1073/pnas.92.18.8343

N. Signoret, J. Oldridge, A. Pelchen-matthews, P. J. Klasse, T. Tran et al., Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4, The Journal of Cell Biology, vol.267, issue.3, pp.651-664, 1997.
DOI : 10.1074/jbc.271.31.18302

A. G. Roseberry and M. M. Hosey, Muscarinic Acetylcholine Receptors, Journal of Biological Chemistry, vol.49, issue.47, pp.33671-33676, 1999.
DOI : 10.1074/jbc.273.9.5323

M. J. Shapiro, J. Trejo, D. Zeng, and S. R. Coughlin, Role of the Thrombin Receptor's Cytoplasmic Tail in Intracellular Trafficking, Journal of Biological Chemistry, vol.269, issue.51, pp.32874-32880, 1996.
DOI : 10.1126/science.2163110

A. Fraile-ramos, T. N. Kledal, A. Pelchen-matthews, K. Bowers, T. W. Schwartz et al., The Human Cytomegalovirus US28 Protein Is Located in Endocytic Vesicles and Undergoes Constitutive Endocytosis and Recycling, Molecular Biology of the Cell, vol.12, issue.6, pp.1737-1749, 2001.
DOI : 10.1091/mbc.12.6.1737

P. A. Stevens, N. Bevan, S. Rees, and G. Milligan, -Adrenoceptor, Molecular Pharmacology, vol.58, issue.2, pp.438-448, 2000.
DOI : 10.1124/mol.58.2.438

S. Morisset, A. Rouleau, X. Ligneau, F. Gbahou, J. Tardivel-lacombe et al., High constitutive activity of native H3 receptors regulates histamine neurons in brain, Nature, vol.57, issue.6814, pp.860-864, 2000.
DOI : 10.1016/S0006-2952(98)00378-5

C. Haskell-luevano and E. K. Monck, Agouti-related protein functions as an inverse agonist at a constitutively active brain melanocortin-4 receptor, Regulatory Peptides, vol.99, issue.1, pp.1-7, 2001.
DOI : 10.1016/S0167-0115(01)00234-8