Alternative models for QTL detection in livestock. I. General introduction

J.M. Elsen (1) , B. Mangin (2) , B. Goffinet (2) , D. Boichard (3) , P. Le Roy (3)

1 SAGA - Station d'Amélioration Génétique des Animaux
2 UBIA - Unité de Biométrie et Intelligence Artificielle (ancêtre de MIAT)
3 SGQA - Station de Génétique Quantitative et Appliquée

In a series of papers, alternative models for QTL detection in livestock are proposed and their properties evaluated using simulations. This first paper describes the basic model used, applied to independent half-sib families, with marker phenotypes measured for a two or three generation pedigree and quantitative trait phenotypes measured only for the last generation. Hypotheses are given and the formulae for calculating the likelihood are fully described. Different alternatives to this basic model were studied, including variation in the performance modelling and consideration of full-sib families. Their main features are discussed here and their influence on the result illustrated by means of a numerical example

Mots clés: QTL DETECTION; MAXIMUM LIKELIHOOD; MAXIMUM DE VRAISEMBLANCE

Domaines: Génétique animale

J.M. Elsen, B. Mangin, B. Goffinet, D. Boichard, P. Le Roy. Alternative models for QTL detection in livestock. I. General introduction. Genetics Selection Evolution, 1999, 31, pp.213-224. ⟨hal-00199719⟩