HAL will be down for maintenance from Friday, June 10 at 4pm through Monday, June 13 at 9am. More information
Skip to Main content Skip to Navigation
Journal articles

Peptide immobilization on amine-terminated boron-doped diamond surfaces.

Abstract : This paper reports on the formation and characterization of semicarbazide termination on aminated boron-doped diamond (BDD) surfaces, and further prepn. of peptide microarray through site-specific a-oxo semicarbazone ligation. Hydrogen-terminated BDD electrodes were first aminated using NH3 plasma treatment and then reacted with triphosgene and Fmoc-protected (Fmoc = 9-fluorenylmethoxycarbonyl) hydrazine to yield a protected semicarbazide termination. Subsequent deprotection and chem. reaction with glyoxylyl peptides led to the covalent immobilization of the peptides on the surface through site-specific ligation. The resulting surfaces were characterized using XPS and fluorescence measurements.
Document type :
Journal articles
Complete list of metadata

https://hal.archives-ouvertes.fr/hal-00179759
Contributor : Leon Gengembre Connect in order to contact the contributor
Submitted on : Tuesday, October 16, 2007 - 3:37:35 PM
Last modification on : Wednesday, March 23, 2022 - 3:50:36 PM

Links full text

Identifiers

Citation

Leon Gengembre, Rabah Boukherroub, Yannick Coffinier, Didier Delabouglise, Remi Desmet, et al.. Peptide immobilization on amine-terminated boron-doped diamond surfaces.. Langmuir, American Chemical Society, 2007, 23 (8), pp.4494-4497. ⟨10.1021/la063440y⟩. ⟨hal-00179759⟩

Share

Metrics

Record views

123