N(1)-Arylsulfonyl-N(2)-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: a new class of calcilytic agents acting at the calcium-sensing receptor.

Albane Kessler (1) , Hélène Faure (2, 3) , Marie Cécile Roussanne (1) , Sandrine Ferry (2, 3) , Martial Ruat (2, 3) , Philippe Dauban (1) , Robert H. Dodd (1)

1 ICSN - Institut de Chimie des Substances Naturelles
2 NBCM - Laboratoire de neurobiologie cellulaire et moléculaire
3 INAF - Institut de Neurobiologie Alfred Fessard

Mots clés: Calcium; Ligand design; Receptors; Structure-activity relationships; Sulfonamides

Domaines: Neurosciences [q-bio.NC]

Albane Kessler, Hélène Faure, Marie Cécile Roussanne, Sandrine Ferry, Martial Ruat, et al.. N(1)-Arylsulfonyl-N(2)-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: a new class of calcilytic agents acting at the calcium-sensing receptor.. ChemBioChem, 2004, 5 (8), pp.1131-6. ⟨10.1002/cbic.200400049⟩. ⟨hal-00169777⟩