Abstract : We propose a grid programming approach using the ProActive middleware. The proposed strategy addresses several grid concerns, which we have classified into three categories. I. Grid Infrastructure which handles the resource acquisition and creation using deployment descriptors and Peer-to-Peer. II. Grid Technical Services which can provide non-functional transparent services like: fault tolerance, load balancing, and file transfer. III. Grid Higher Level programming with: group communication and hierarchical components. We have validated our approach with several grid programming experiences running applications on heterogeneous Grid resource using more than 1000 CPUs.