Chemical Shift Imaging (CSI) by precise object displacement

Sebastien Leclerc (1, 2) , Gregory Trausch (1) , Benoit Cordier (2) , Denis Grandclaude (1) , Alain Retournard (1) , Jacques Fraissard (3) , Daniel Canet (3)

1 LMRMN - Laboratoire de Méthodologie en Résonance Magnétique Nucléaire
2 LEMTA - Laboratoire d'Energétique et Mécanique Théorique et Appliquée
3 PMMH - Physique et mécanique des milieux hétérogenes (UMR 7636)

A mechanical device (NMR lift) has been built for displacing vertically an object (typically a NMR sample tube) inside the NMR probe with an accuracy of 1 Μm. A series of single pulse experiments are performed for incremented vertical positions of the sample. With a sufficiently spatially selective rf field, one obtains chemical shift information along the displacement direction (one dimensional Chemical Shift Imaging – CSI). Knowing the vertical radio-frequency (rf) field profile (the amplitude of the rf field along the vertical direction) makes it possible to reconstruct the spectrum associated with all the slices corresponding to consecutive sample positions and to improve the spatial resolution, which is simply related to the accuracy of the displacement device. Besides tests performed on phantoms, the method has been applied to solvent penetration in polymers and to benzene diffusion in a heterogeneous zeolite medium.

Mots clés: NMR; CSI; 1H; mechanical device; imbibed polymer; zeolite; diffusion

Domaines: Chimie théorique et/ou physique

Sebastien Leclerc, Gregory Trausch, Benoit Cordier, Denis Grandclaude, Alain Retournard, et al.. Chemical Shift Imaging (CSI) by precise object displacement. Magnetic Resonance in Chemistry, 2006, 44 (3), pp.311-317. ⟨10.1002/mrc.1757⟩. ⟨hal-00124995⟩