Poly(ethyl glycol) surface coated magnetic particles

Christophe Flesch (1) , Yves Unterfinger (1) , Elodie Bourgeat-Lami (2) , Etienne Duguet (3) , Christelle Delaite (1) , Philippe Dumas (1)

1 ICSI - Institut de Chimie et des Surfaces et Interfaces
2 LCPP - Laboratoire de chimie et procédés de polymérisation
3 ICMCB - Institut de Chimie de la Matière Condensée de Bordeaux

A methacrylate-functionalized poly(ethylene glycol) macromonomer was copolymerized at the surface of methacrylate-derivatized maghemite nanoparticles. After silylation of the magnetic core with methacryloxypropyltrimethoxysilane, two grafting procedures based on either a direct copolymerization reaction in water or an inverse emulsion polymerization were compared. A direct copolymerization led to low polymer surface amounts, whereas an inverse emulsion process allowed nanocomposite particles containing up to 90 wt.-% polymer to be obtained.

Mots clés: Biocompatibility; Macromonomers; Maghemite; Nanocomposites; Poly(ethylene glycol)

Domaines: Matériaux

Christophe Flesch, Yves Unterfinger, Elodie Bourgeat-Lami, Etienne Duguet, Christelle Delaite, et al.. Poly(ethyl glycol) surface coated magnetic particles. Macromolecular Rapid Communications, 2005, vol. 26, n° 18,, p. 1494-1498. ⟨10.1002/marc.200500402⟩. ⟨hal-00096691⟩