Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus.

Hugues Bedouelle (1) , Laurent Belkadi (1) , Patrick England (1) , J. Inaki Guijarro (2) , Olesia Lisova (1) , Agathe Urvoas (1) , Muriel Delepierre (2) , Philippe Thullier (3)

1 HVAIBD - Hôtes, vecteurs et agents infectieux : biologie et dynamique
2 Bioinformatique Structurale
3 Département de Biologie des Agents Transmissibles

Mots clés: antibody; complementary determining region; dengue virus; gene rearrangement; molecular recognition

Domaines: Autre [q-bio.OT]; Biochimie [q-bio.BM]

Hugues Bedouelle, Laurent Belkadi, Patrick England, J. Inaki Guijarro, Olesia Lisova, et al.. Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus.. FEBS Journal, 2006, 273 (1), pp.34-46. ⟨10.1111/j.1742-4658.2005.05045.x⟩. ⟨hal-00018744⟩