Structure cristalline de la L-leucyl-L-leucyl-L-tyrosine chlorhydraté

Jean Delettré (1) , Jean Berthou (1) , Alain Lifchitz (1) , Pierre Jollès (2)

1 LMCP - Laboratoire de minéralogie, cristallographie de Paris
2 LCBPT - UMR 8601 - Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques

C₂₁H₃₄N₃O₅⁺.Cl^-, M_r = 444.0, orthorhombic, P2₁2₁2₁, a = 26.074 (5), b = 17.591 (4), c = 5.224 (2) Å, V = 2396.1 (10) ų, Z = 4, Cu Kα, λ = 1.5418 Å, µ = 1.71 mm^-1, F(000) = 952, D_x = 1.231 Mg m^-3, room temperature, final R = 0.080 and wR = 0.070 for all 2439 reflections [(sinθ)/λ > 0.03 Å^-1]. The peptide groups are planar; torsion angles (-101 and -88°) indicate a roughly helical structure. The peptide bonds have a trans conformation. The crystal structure is stabilized by a network of hydrogen bonds.

Mots clés: crystal structure; peptide

Domaines: Science des matériaux [cond-mat.mtrl-sci]; Biochimie [q-bio.BM]

Jean Delettré, Jean Berthou, Alain Lifchitz, Pierre Jollès. Structure cristalline de la L-leucyl-L-leucyl-L-tyrosine chlorhydraté. Acta Crystallographica Section C : Structural Chemistry [2014-..], 1988, 44, pp.905-907. ⟨10.1107/S0108270188000940⟩. ⟨hal-00015166⟩