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Electrical Sensing of sickled red blood cells subpopulations in microfluidic device

Abstract : This paper discusses the electrical sensing of red blood cell (RBC) rigidity due to Hemoglobin S (HbS) polymerization in sickle cell disease. For this purpose sickle RBCs subpopulations, differentiated by cell density, were flown through a microfluidic device equipped with integrated microelectrodes. Differences in transit time and electrical blockade were observed and analyzed.
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https://hal.archives-ouvertes.fr/hal-03078878
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Submitted on : Monday, January 4, 2021 - 5:43:22 PM
Last modification on : Wednesday, November 3, 2021 - 4:31:07 AM
Long-term archiving on: : Monday, April 5, 2021 - 6:39:57 PM

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  • HAL Id : hal-03078878, version 1

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Tieying Xu, Maria Lizarralde-Iragorri, Jean Roman, Emile Martincic, Valentine Brousse, et al.. Electrical Sensing of sickled red blood cells subpopulations in microfluidic device. MicroTAS, Oct 2020, on-line, France. ⟨hal-03078878⟩

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