High yield preparation of purpurin-18 from Spirulina maxima

Abstract : Purpurin-18, a derivative of chlorophyll, is an interesting dihydroporphyrin for generating photosensitizers such as purpurinimides which absorb light in the 700-850 nm range and which display efficient anti-tumor activity. To promote extensive utilization of Pp-18 as a starting material for the preparation of new photosensitizers, a simple and rapid method for obtaining this chlorin in high yield from Spirulina maxima is described. Optimized experimental conditions were determined using a Latin square design of experiments.
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Soumis le : mercredi 16 mai 2012 - 10:45:50
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Nicolas Drogat, Matthieu Barrière, Robert Granet, Vincent Sol, Pierre Krausz. High yield preparation of purpurin-18 from Spirulina maxima. Dyes and Pigments, Elsevier, 2011, 88 (1), pp.125-127. ⟨10.1016/j.dyepig.2010.05.006⟩. ⟨hal-00697766⟩



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