21 articles – 668 Notices  [english version]
HAL : hal-00643477, version 1

Fiche détaillée  Récupérer au format
Biomedical Engineering, IEEE Transactions on 58, 1 (2010) pp. 207-214
Characterization of a 50 Ohms Exposure Set-up for High Voltage Nanosecond Pulsed Electric Field Bioexperiments
Mohamad Kenaan 1, Saad El Amari 1, A. Silve, Caterina Merla 1, L. Mir, Vincent Couderc 1, Delia Arnaud-Cormos 1, Philippe Lévêque 1
(27/09/2010)

An exposure system for a nanosecond pulsed electric field is presented and completely characterized in this paper. It is composed of a high-voltage generator and an applicator: the biological cuvette. The applied pulses have high intensities (up to 5 kV), short durations (3 and 10 ns), and different shapes (square, bipolar). A frequency characterization of the cuvette is carried out based on both an analytical model and experimental measurements (S11) in order to determine its matching bandwidth. High voltage measurements in the time domain are performed. Results show that the cuvette is well adapted to 10-ns pulses and limited to those of 3 ns. The rise/fall times of the pulses should not be less than 1.5 ns. In addition, numerical calculation providing voltage distribution within the cuvette is performed using an in-house finite-difference time-domain code. A good level of voltage homogeneity across the cuvette electrodes is obtained, as well as consistency with experimental data for all the applied pulses.
1 :  XLIM (XLIM)
CNRS : UMR6172 – Université de Limoges
OSA
PHOTONIQUE