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Journal of Medical Systems 34, 5 (2010) 815-828
3D Image Analysis and Artificial Intelligence for Bone Disease Classification
Abdurrahim Akgundogdu 1, Rachid Jennane ( ) 2, Gabriel Aufort 2, Claude-Laurent Benhamou 3, Osman Nuri Ucan 1
(10/2010)

In order to prevent bone fractures due to disease and ageing of the population, and to detect problems while still in their early stages, 3D bone micro architecture needs to be investigated and characterized. Here, we have developed various image processing and simulation techniques to investigate bone micro architecture and its mechanical stiffness. We have evaluated morphological, topological and mechanical bone features using artificial intelligence methods. A clinical study is carried out on two populations of arthritic and osteoporotic bone samples. The performances of Adaptive Neuro Fuzzy Inference System (ANFIS), Support Vector Machines (SVM) and Genetic Algorithm (GA) in classifying the different samples have been compared. Results show that the best separation success (100 %) is achieved with Genetic Algorithm.
1 :  Department of Electrical and Electronics Eng
Istanbul University
2 :  Laboratoire PRISME (PRISME)
Université d'Orléans : EA4229 – ENSI Bourges
3 :  Caractérisation du tissu osseux par imagerie : techniques et applications
INSERM : U658 – CHR Orléans – Université d'Orléans
Istanbul University
IRAuS
Ludia Inc.
INSERM U658
Dept. of Electrical Electronics Engineering (Istanbul Aydin University)
Sciences de l'ingénieur/Traitement du signal et de l'image

Informatique/Traitement du signal et de l'image
Trabecular bone – Hybrid Skeleton Graph Analysis – SVM – GA – ANFIS
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