2935 articles  [version française]
HAL: hal-00555287, version 2

Detailed view  Export this paper
Journal of Theoretical Biology (2012) Journal of Theoretical Biology 294 (2012) 114-121
Available versions:
Mathematical Modeling of Transport and Degradation of Feedstuffs in the Small Intestine
Masoomeh Taghipoor ( ) 1, 2, 3, Philippe Lescoat 2, Christine Georgelin 1, 3, Jean-René Licois 1, 3, Guy Barles 1, 3
For the PEPS CNRS-INRA "Comprehension et Modelisation du devenir de l'aliment dans le tube digestif" collaboration(s)
(2012)

We describe a mathematical modeling of the digestion in the small intestine. The main interest of our work is to consider, at the same time, different aspects of the digestion i.e. the transport of the bolus all along the intestine, feedstuffs degradation according to the enzymes and local physical conditions, and nutrients absorption. A system of coupled ordinary differential equations is used to model these phenomena. The major unknowns of this system are the position of the bolus and its composition. This system of equations is solved numerically. We present different numerical computations for the degradation, absorption and transport of the bolus with acceptable accuracy with experimental data. The main feature and interest of this model are its generality. Even if we are at an early stage of development, our approach can be adapted to treat any kind of feedstuffs in any non-ruminant animal to predict the composition and velocity of bolus in the small intestine.
1:  Laboratoire de Mathématiques et Physique Théorique (LMPT)
CNRS : UMR6083 – Université François Rabelais - Tours
2:  Recherches Avicoles (SRA)
Institut national de la recherche agronomique (INRA) : UR0083
3:  Fédération de recherche Denis Poisson (FRDP)
CNRS : FR2964 – Université d'Orléans – Université François Rabelais - Tours
Mathematics/Dynamical Systems

Life Sciences/Food and Nutrition
Digestion – Small Intestine – Modeling – Ordinary Differential Equations – Enzymatic Degradation – Transport
Attached file list to this document: 
PDF
manuscript2.pdf(618.3 KB)