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Journal of Biological Dynamics (2011) 10.1080/17513758.2011.568071
Passing to the limit 2D-1D in a model for metastatic growth
Sebastien Benzekry 1, 2
(2011-05-03)

We prove the convergence of a family of solutions to a two-dimensional transport equation with a nonlocal boundary condition modeling the evolution of a population of metastases. We show that when the data of the repartition along the boundary tends to a dirac mass then the solution of the associated problem converges and we derive a simple expression for the limit in term of the solution of a 1D equation. This result permits to improve the computational time needed to simulate the model.
1:  Laboratoire d'Analyse, Topologie, Probabilités (LATP)
CNRS : UMR6632 – Université de Provence - Aix-Marseille I – Université Paul Cézanne - Aix-Marseille III
2:  Relations Hôtes Parasites Pharmacologie et Thérapeutique (UMR MD3)
Institut de Recherche Biomédicale des Armées – Université de la Méditerranée - Aix-Marseille II
Mathematics/Analysis of PDEs
Structured population dynamics – Cancer modeling – Angiogenesis
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