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18th Congress of the European Society of Biomechanics, Portugal (2012)

A mechanical and numerical approach applied to epithelium topology and development

Yoann Chélin 1, Karim Azzag 2, Patrick Canadas (  Corresponding author ) 1, Stephen Baghidiguian 2, Bernard Maurin 1

(2012)

A key decisive in the understanding of morphogenesis processes concerns the description of the development of regular topolgy epithelial tissue as usually observed. The cell pattern is characterized by the average number of the cell neighbours (frequency distribution). Nevertheless, the mechanisms of packing geometry formation, such as the follicular tissue surrounding the Ciona Intestinalis egg, are poorly understood. In order to study further this epithelium development, we made a numerical model based on the mechanics of divided media. Here we propose two scenarii: one governed by cell accretion and the other managed by cell division. With the first one, we explore the influence of the growth rate and with the second one the incidence of mitosis.

1:	Laboratoire de mécanique et génie civil (LMGC)
	CNRS : UMR5508 – Université Montpellier II - Sciences et techniques
2:	Institut des Sciences de l'Evolution - Montpellier (ISEM)
	CNRS : UMR5554 – Université Montpellier II - Sciences et techniques – Institut de recherche pour le développement [IRD] : UMR226

Research team: Conception en Structures Couplages en Géomécanique et Biomécanique

Subject

:

Engineering Sciences/Mechanics/Biomechanics Physics/Mechanics/Biomechanics

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From: François Gibier <>

Submitted on: Wednesday, 11 April 2012 14:00:08

Updated on: Wednesday, 11 April 2012 14:20:59