Innate and adaptive immune responses following PD‐L1 blockade in treating chronic murine alveolar echinococcosis

Fadi Jebbawi (1) , Anne-Pauline Bellanger (2, 3) , Britta Lunström-Stadelmann (4) , Reto Rufener (4) , Michel Dosch (1) , Christine Goepfert (4) , Bruno Gottstein (5) , Laurence Millon (2, 3) , Denis Grandgirard (5) , Stephen Leib (5) , Guido Beldi (1) , Junhua Wang (5, 4)

1 Department of Visceral and Transplant Surgery
2 LCE - Laboratoire Chrono-environnement (UMR 6249)
3 Service de parasitologie et mycologie [CHRU de Besançon]
4 UNIBE - Universität Bern / University of Bern
5 Institute for Infectious Diseases, Faculty of Medicine, University of Berne, 3001 Berne, Switzerland

Programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) immune checkpoint blockade are efficacious in certain cancer therapies.

Mots clés: Echinococcus multilocularis; albendazole; anti-PD-L1; immunotherapy

Domaines: Santé

Fadi Jebbawi, Anne-Pauline Bellanger, Britta Lunström-Stadelmann, Reto Rufener, Michel Dosch, et al.. Innate and adaptive immune responses following PD‐L1 blockade in treating chronic murine alveolar echinococcosis. Parasite Immunology, 2021, 43 (8), pp.e12834. ⟨10.1111/pim.12834⟩. ⟨hal-03315204⟩