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Article Dans Une Revue Journal of Infection Année : 2020

Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound?

Résumé

For the first 3 months of COVID-19 pandemic, COVID-19 was expected to be an immunizing non-relapsing disease. We report a national case series of 11 virologically-confirmed COVID-19 patients having experienced a second clinically- and virologically-confirmed acute COVID-19 episode. According to the clinical history, we discuss either re-infection or reactivation hypothesis. Larger studies including further virological, immunological and epidemiologic data are needed to understand the mechanisms of these recurrences.

Dates et versions

hal-03080302 , version 1 (17-12-2020)

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Marie Gousseff, Pauline Penot, Laure Gallay, Dominique Batisse, Nicolas Benech, et al.. Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound?. Journal of Infection, 2020, 81 (5), pp.816-846. ⟨10.1016/j.jinf.2020.06.073⟩. ⟨hal-03080302⟩
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