Do contact precautions reduce the incidence of ICU-acquired Pseudomonas aeruginosa infections? The DPCPYO cluster-randomized crossover trial

Céline Slekovec (1, 2) , jerome robert (3) , Philippe Berthelot (4) , Nathalie van Der Mee-Marquet (5) , Anne-Marie Rogues (6, 7) , Véronique Derouin (8) , Pascal Cholley (1, 2) , Xavier Bertrand (2, 1) , Houssein Gbaguidi-Haore (1, 2)

1 LCE - Laboratoire Chrono-environnement (UMR 6249)
2 CHRU Besançon - Centre Hospitalier Régional Universitaire de Besançon
3 CIMI - Centre d'Immunologie et des Maladies Infectieuses
4 CHU ST-E - Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne]
5 Hôpital Bretonneau
6 Hôpital Pellegrin, CHU de Bordeaux
7 BPH - Bordeaux population health
8 AP-HP - Hôpital Antoine Béclère, Assistance Publique - Hôpitaux de Paris

Issue of contact precautions as contributory factors for reducing P. aeruginosa (Pa) infections in intensive care units (ICUs) remains questioned. We evaluated the impact of the addition of contact precautions to standard precautions for Pa-positive patients on the incidence of ICU-acquired Pa infections.

Mots clés: Pseudomonas aeruginosa; Contact precautions; ICU; PFGE; Patient-to-patient transmission

Domaines: Médecine humaine et pathologie; Microbiologie et Parasitologie

Céline Slekovec, jerome robert, Philippe Berthelot, Nathalie van Der Mee-Marquet, Anne-Marie Rogues, et al.. Do contact precautions reduce the incidence of ICU-acquired Pseudomonas aeruginosa infections? The DPCPYO cluster-randomized crossover trial. Clinical Infectious Diseases, 2020, ⟨10.1093/cid/ciaa1663⟩. ⟨hal-03043921⟩