%0 Conference Paper
%F Poster 
%T Inferring data on cilia spatiotemporal coordination through bronchial epithelium imaging.
%+ Laboratoire Charles Coulomb (L2C)
%+ Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp)
%+ Matière Molle
%+ Service d'allergologie et de pneumologie [Hôpital Arnaud de Villeneuve]
%A Jory, Myriam
%A Fort, Aurélie
%A Casanellas Vilageliu, Laura
%A Vachier, Isabelle
%A Bourdin, Arnaud
%A Massiera, Gladys
%< sans comité de lecture
%Z L2C:18-448
%B Workshop: Physics of integrated biological systems
%C Cargèse, France
%8 2018-09-11
%D 2018
%K Cilia
%K Coordination
%K Human bronchial epithelium
%K Videomicroscopy
%K Image processing
%Z Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph]Poster communications
%X The mucociliary function of the bronchial epithelium ensures the continuous clearance of the respiratory system. This function relies on two main elements: mucus properties and cilia beating coordination. We work on high speed optical microscopy videos of Human bronchial epithelium from ALI (Air-liquid interface) cultures. We present here a technique based on the tracking of each cilium and on the spatiotemporal analysis of the obtained trajectories. To relate each cilium to its corresponding cell, a clustering method is used. The spatiotemporal coordination can than be quantified both, inside and in-between ciliated cells. In addition the physical parameters can be mapped to observe the heterogeneity of the cilia activity and compare different pathologies.
%G English
%Z Projet de thèse: "Approche biophysique de la fonction mucociliaire: rhéologie du mucus et coordination ciliaireCollaboration avec le CHU de Montpellier
%L hal-02062133
%U https://hal.science/hal-02062133
%~ CNRS
%~ L2C
%~ MIPS
%~ BS
%~ UNIV-MONTPELLIER
%~ PHYMEDEXP
%~ UM-2015-2021