Invariant based control of induction and maintenance phases for anesthesia

Mirko Fiacchini (1) , Isabelle Queinnec (2) , Sophie Tarbouriech (2) , Michel Mazerolles (3)

1 GIPSA-SYSCO - GIPSA - Systèmes non linéaires et complexité
2 LAAS-MAC - Équipe Méthodes et Algorithmes en Commande
3 Pôle Anesthésie Réanimation [CHU de Toulouse]

Set theory and invariant sets are the key ingredients used in this paper to address the control problem of general anesthesia. The paper is dedicated to adapt such tools in order to validate the multi-phase control law used in practice from the induction phase corresponding to the administration of an open-loop bolus dose to the maintenance phase of the depth of hypnosis during the surgical operation.

Mots clés: Anesthesia; biomedical systems; constrained control; computational methods

Domaines: Automatique / Robotique

Mirko Fiacchini, Isabelle Queinnec, Sophie Tarbouriech, Michel Mazerolles. Invariant based control of induction and maintenance phases for anesthesia. FOSBE 2016 - 6th IFAC Conference on Foundations of Systems Biology in Engineering, IFAC, Oct 2016, Magdeburg, Germany. pp.50 - 55, ⟨10.1016/j.ifacol.2016.12.102⟩. ⟨hal-01474513⟩