%0 Journal Article
%T Comparison between resting state fMRI networks and responsive cortical stimulations in glioma patients
%+ Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)
%+ Institut de Génomique Fonctionnelle (IGF)
%+ Hôpital Gui de Chauliac [CHU Montpellier]
%+ Institut des Neurosciences de Montpellier (INM)
%+ Neurochirurgie [Hôpital Gui de Chauliac]
%+ Institut d’Imagerie Fonctionnelle Humaine [CHU Montpellier] (I2FH)
%+ Control of Artificial Movement and Intuitive Neuroprosthesis (CAMIN)
%+ Laboratoire Charles Coulomb (L2C)
%A Cochereau, Jérôme
%A Deverdun, Jeremy
%A Herbet, Guillaume
%A Charroud, Céline
%A Boyer, Anthony
%A Moritz-Gasser, Sylvie
%A Le Bars, Emmanuelle
%A Molino, François
%A Bonafé, Alain
%A Menjot de Champfleur, Nicolas
%A Duffau, Hugues
%< avec comité de lecture
%Z L2C:16-248
%@ 1065-9471
%J Human Brain Mapping
%I Wiley
%V 37
%N 11
%P 3721-3732
%8 2016-11
%D 2016
%R 10.1002/hbm.23270
%M 27246771
%K Functional magnetic resonance imaging
%K resting-state fMRI
%K brain mapping
%K sensorimotor cortex
%K language
%K glioma
%K neurosurgery
%Z Computer Science [cs]/Bioinformatics [q-bio.QM]Journal articles
%X To validate the functional relevance of resting state networks (RSNs) by means of a comparison of resting state connectivity (RSC) between language regions elicited by direct cortical stimulation versus RSC between random regions; and to evaluate the accuracy of resting state fMRI in surgical planning by assessing the overlap between RSNs and intraoperative functional mapping results. Sensorimotor and language eloquent sites were identified by direct electrical cortical stimulation in 98 patients with a diffuse low-grade glioma. A seed to voxel analysis with inter-language stimulation point connectivity versus inter-random ROIs connectivity was performed (19 patients). An independant component analysis (ICA) was also applied to rsfMRI data. Language and sensorimotor components were selected over 20 independent components and compared to the corresponding stimulation points and resected cortex masks (31 and 90 patients, respectively). The significantly higher RSC between language seeds than between random seeds validated the functional relevance of RSC. ICA partly succeeded to distinguish eloquent versus surgically removable areas and may be possibly used as a complementary tool to intraoperative mapping.
%G English
%2 https://hal.science/hal-01446083/document
%2 https://hal.science/hal-01446083/file/HBM-37-3721.pdf
%L hal-01446083
%U https://hal.science/hal-01446083
%~ INSERM
%~ CNRS
%~ INRIA
%~ INRIA-SOPHIA
%~ INM
%~ IGF
%~ INRIASO
%~ INRIA_TEST
%~ L2C
%~ TESTALAIN1
%~ LIRMM
%~ INRIA2
%~ CAMIN
%~ MIPS
%~ BS
%~ UNIV-MONTPELLIER
%~ UM-2015-2021
%~ INRIAARTDOI
%~ FRM