Marine Natural Products from New Caledonia—A Review

Sofia-Eléna Motuhi (1, 2) , Mohamed Mehiri (3) , Claude Payri (1) , Stéphane La Barre (4) , Stéphane Bach (2)

1 LabEX CORAIL - Laboratoire d'Excellence CORAIL
2 P3H - Phophorylation de protéines et Pathologies Humaines
3 ICN - Institut de Chimie de Nice
4 LBI2M - Laboratoire de Biologie Intégrative des Modèles Marins

Marine micro-and macroorganisms are well known to produce metabolites with high biotechnological potential. Nearly 40 years of systematic prospecting all around the New Caledonia archipelago and several successive research programs have uncovered new chemical leads from benthic and planktonic organisms. After species identification, biological and/or pharmaceutical analyses are performed on marine organisms to assess their bioactivities. A total of 3582 genera, 1107 families and 9372 species have been surveyed and more than 350 novel molecular structures have been identified. Along with their bioactivities that hold promise for therapeutic applications, most of these molecules are also potentially useful for cosmetics and food biotechnology. This review highlights the tremendous marine diversity in New Caledonia, and offers an outline of the vast possibilities for natural products, especially in the interest of pursuing collaborative fundamental research programs and developing local biotechnology programs.

Mots clés: New Caledonia; marine biodiversity; bioactive molecules pipeline; chemodiversity; coral reefs

Domaines: Océan, Atmosphère

Sofia-Eléna Motuhi, Mohamed Mehiri, Claude Payri, Stéphane La Barre, Stéphane Bach. Marine Natural Products from New Caledonia—A Review. Marine drugs, 2016, 14 (3), pp.58. ⟨10.3390/md14030058⟩. ⟨hal-01292225⟩