%0 Journal Article
%T Enhanced potassium selectivity in a bioinspired solid nanopore
%+ Institut Européen des membranes (IEM)
%+ Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier (ICGM ICMMM)
%+ Laboratoire Charles Coulomb (L2C)
%A Picaud, Fabien
%A Kraszewski, Sebastian
%A Ramseyer, Christophe
%A Balme, Sebastien
%A Dejardin, Philippe
%A Janot, Jean Marc
%A Henn, Francois
%< avec comité de lecture
%Z L2C:13-393
%@ 1463-9076
%J Physical Chemistry Chemical Physics
%I Royal Society of Chemistry
%V 15
%N 45
%P 19601-19607
%8 2013-07-31
%D 2013
%R 10.1039/c3cp52123k
%Z Chemical Sciences/Theoretical and/or physical chemistry
%Z Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]Journal articles
%X Biological ion channels present unique ionic properties. They can be highly permeable to ions, while selecting only one type of ions, without external energy supply. An important research field has been developed to transfer these properties to solid state nanoporous membranes in order to develop artificial biomimetic nanofilters. One of the promising ways to develop biomimetic structures is based on the direct insertion of the gramicidin A, i.e. an ionic channel, inside a nanopore. Experiments have recently proved the feasibility of such a hybrid membrane with very interesting results regarding the ionic selectivity. Here, we propose to interpret these experiments using theoretical molecular dynamic simulations which allow us to analyze more profoundly the structures of the proteins confined inside the nanopore and the relation between their conformation and the observed ionic properties.
%G English
%L hal-01241275
%U https://hal.science/hal-01241275
%~ CNRS
%~ UNIV-MONTP1
%~ UNIV-MONTP2
%~ ENSC-MONTPELLIER
%~ ICG
%~ IEM
%~ L2C
%~ INC-CNRS
%~ MIPS
%~ CHIMIE
%~ UNIV-MONTPELLIER
%~ ANR
%~ UM1-UM2
%~ UM-2015-2021
%~ TEST2-HALCNRS