Prevalence of Escherichia coli sequence type 131 and its H30 subclone among E. coli isolates in a French hospital.

Jeremy Lafolie (1) , Marie-Hélène Nicolas-Chanoine , Frédéric Grenouillet (1, 2) , Didier Hocquet (1, 2) , Xavier Bertrand (1, 2)

1 CHRU Besançon - Centre Hospitalier Régional Universitaire de Besançon
2 LCE - Laboratoire Chrono-environnement (UMR 6249)

The prevalence of Escherichia coli sequence type 131 (ST131) and its subclone H30 was assessed among a collection of 490 E. coli isolated in 2013 in a French university hospital. The prevalence of ST131 was 4% among bloodstream isolates (regardless of antimicrobial resistance) and 17.2% among extended-spectrum β-lactamase (ESBL)-producing isolates. Although a much lower prevalence of ST131 was found among bloodstream E. coli isolates compared with other countries, a large predominance of H30 subclone within ST131 was confirmed. It was also confirmed that, among ESBL-producing E. coli, ST131 isolates were more frequently resistant to amoxicillin/clavulanic acid, ceftazidime, fluoroquinolones and aminoglycosides than non-ST131 isolates.

Domaines: Bactériologie; Mycologie; Microbiologie et Parasitologie

Jeremy Lafolie, Marie-Hélène Nicolas-Chanoine, Frédéric Grenouillet, Didier Hocquet, Xavier Bertrand. Prevalence of Escherichia coli sequence type 131 and its H30 subclone among E. coli isolates in a French hospital.. International Journal of Antimicrobial Agents, 2014, 44 (5), pp.466-8. ⟨hal-01114505⟩