%0 Journal Article
%T Polydispersity analysis of Taylor dispersion data: the cumulant method
%+ Laboratoire Charles Coulomb (L2C)
%+ Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM)
%+ Physique et mécanique des milieux hétérogenes (UMR 7636) (PMMH)
%A Cipelletti, Luca
%A Biron, Jean-Philippe
%A Martin, Michel
%A Cottet, Hervé
%Z Chercheurs d'Avenir from the Institut Universitaire de France (2011−2016)
%Z 41 pages (including Supporting Information), 5 figures (+ 7 figs. in the Supporting Information)
%< avec comité de lecture
%@ 0003-2700
%J Analytical Chemistry
%I American Chemical Society
%V 86
%N 13
%P 6471-6478
%8 2014-06-17
%D 2014
%Z 1408.6085
%R 10.1021/ac501115y
%K taylor dispersion analysis
%K polydispersity
%K polymer
%K cumulant
%Z Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft]Journal articles
%X Taylor dispersion analysis is an increasingly popular characterization method that measures the diffusion coefficient, and hence the hydrodynamic radius, of (bio)polymers, nanoparticles or even small molecules. In this work, we describe an extension to current data analysis schemes that allows size polydispersity to be quantified for an arbitrary sample, thereby significantly enhancing the potentiality of Taylor dispersion analysis. The method is based on a cumulant development similar to that used for the analysis of dynamic light scattering data. Specific challenges posed by the cumulant analysis of Taylor dispersion data are discussed, and practical ways to address them are proposed. We successfully test this new method by analyzing both simulated and experimental data for solutions of moderately polydisperse polymers and polymer mixtures.
%G English
%2 https://hal.science/hal-01058494/document
%2 https://hal.science/hal-01058494/file/1408.6085%20%281%29.pdf
%L hal-01058494
%U https://hal.science/hal-01058494
%~ ESPCI
%~ CNRS
%~ ENSC-MONTPELLIER
%~ PMMH
%~ IBMM
%~ PARISTECH
%~ L2C
%~ LPMMH
%~ INC-CNRS
%~ PSL
%~ MIPS
%~ CHIMIE
%~ UNIV-MONTPELLIER
%~ SORBONNE-UNIVERSITE
%~ SU-INF-2018
%~ SU-SCIENCES
%~ UNIV-PARIS
%~ UP-SCIENCES
%~ ESPCI-PSL
%~ SU-TI
%~ ALLIANCE-SU
%~ UM-2015-2021
%~ TEST2-HALCNRS