Small GTPases of the Rho family and cell transformation.

Philippe Fort (1)

1 CRBM - Centre de recherches de biochimie macromoléculaire

Over the past few years, it has been shown that Rho GTPases play a role in the organisation of the actin cytoskeleton, and also have critical functions in the control of cell proliferation. In the present review, I address the implication of the Rho family in cell transformation and apoptosis, as well as in the regulatory crosstalk between pathways controlled by Rho and Ras proteins.

Domaines: Biologie moléculaire

Philippe Fort. Small GTPases of the Rho family and cell transformation.. Progress in molecular and subcellular biology, 1999, 22, pp.159-81. ⟨hal-00875311⟩